Department of Chemistry, VNIT

Dr. Sujit Kumar Ghosh

Brief Bio

About Me
Prof. Ghosh joined in VNIT, Nagpur in July 2012 as an Associate professor and become full Professor afterwards. He obtained his Ph.D. Degree in Chemistry from Jadavpur University, Kolkata, India in 2004. Before joining at VNIT, he worked in several prestigious institutions in India and USA. He worked in BITS-Pilani Goa, India (as an Assistant Professor), Tata Institute of Fundamental Research (TIFR), Mumbai, India (as a Visiting Fellow), Bowling Green State University, Ohio, USA (as a Post-doctoral research associate) and UPRH, PR, USA (as a Post Doc fellow). His current research interest is Application of Molecular Spectroscopy for Optoelectronic Materials and Theragnostic Drug Development, Biophysical Chemistry & P3: Photophyics, Photochemistry & Photobiology. (Details: http://sujitkghosh.weebly.com/)
Sr. No.DegreeYearSpecializationUniversity
1Visiting Fellow2008BiophotonicsChemical Science Division, Tata Institute of Fundamental research(TIFR), Mumbai-400 005, India. (worked with Prof. Sudipta Maiti )
2Postdoctoral Research Associate2007-2008Single Molecule SpectroscopyCenter for Photochemical Sciences, Dept. Of Chemistry, Bowling Green State University, Ohio, 43403, USA (worked with Prof. H. Peter Lu)
3Postdoctoral Fellow2005-2007Biomedical SciencesDepartment of Chemistry, University of Puerto Rico at Humacao, PR, 00791, USA (worked with Prof. Antonio E. Alegria)
4Ph.D.2000-2004Chemistry and Optical SpectroscopyJadavpur University, Kolkata, India, Thesis Supervisor: Prof. Subhash Chandra Bhattacharya
Phone:Email:Address:
(91) 7122801775 / 1776skghosh@chm.vnit.ac.in, sujitju@yahoo.co.inDepartment of Chemistry, Visvesvaraya National Institute of Technology Nagpur,South Ambazari Road, Nagpur, Maharashtra, 440010, India
Application of Molecular Spectroscopy for Optoelectronic Materials and Theragnostic Drug Development, Biophysical Chemistry, P3: Photophyics, Photochemistry & Photobiology.
We are a group of Physical and Synthetic Chemists; challenging problems at an interface of Chemistry, Physics & Biology using Steady state & Time Resolved Fluorescence Spectroscopy, Fluorescence Anisotropy, Fluorescence Microscopy, Single Molecule Spectroscopy, Confocal Imaging and Fiber Microscopy.
S.No.Paper Citation
44“Achieving the Reverse Intersystem Crossing in Chalcone Based Donor-Acceptor System through Down-Conversion of Triplet Exciton” PiyushSingh, Pradip Pattanayak, PradiptaPurkayastha and Sujit Kumar Ghosh* Chemistry A Eur. J. 29, 64, (2023) e202302587.
43“Water‐Assisted Photoinduced Tautomerization in a Potential Bioactive Semicarbazone Schiff Base” Piyus Singh, Teena Tenna, Kapil Ganorkar and Sujit Kumar Ghosh; Chemistry Select 8 (43) 2023. Nov 2023 e202302869
42“Novel Azapodophyllotoxin Induces DNA Cleavage via Groove Binding: An Advancement in Exploration of Anticancer Activity of a Known Inhibitor of Tubulin Polymerization and Topoisomerase” Smruti Gupta, Ajay Kumar and Sujit Kumar Ghosh*. Chemistry Select 8, 15, (2023) e202204882
41“Switching of Polarity Sensitive Aggregation Pattern of a Thiosemicarbazone based Anticancer Luminophore and its Involvement in Cellular Apoptosis of Human Lungs Cancer Cell Line”; Kapil Ganorkar, Angela Samanta, Soham Mukherjee, Ritika Joshi, Smruti Gupta, Angshuman Sarkar and Sujit Kumar Ghosh* J. Phys. Chem. B 127, 1, (2023), 104–120.
40Effect of artificial sweetener saccharin on lysozyme aggregation: A combined spectroscopic and in silico approach; R Dudure, K. Ganorkar, V. Beldar, Sujit Kumar Ghosh, A.K. Panda, Manojkumar Jadhao, Spectrochimica Acta part A: Bimol Spec. 2023 (290) 122269. Link: https://authors.elsevier.com/c/1gIjf4xB1qeVdS
39“Cryptic Solvation Dynamics of Potential Antineoplastic Azapodophyllotoxin: Short and Long Range Charge Transfer and Distinct H-bonding Motifs Demystify its Swinging Emissive Behaviour”; Smruti Gupta, Kapil Ganorkar, Naina Sehraa, Ajay Kumar, Sujit Kumar Ghosh Journal of Photochemistry and Photobiology A: Chemistry; 2022 (422) 113556
38“Excavating Interaction of a Potential Anticancer Thiosemicarbazone based Bioorganic Ligand in Sudlow Site I of Human Serum Albumin” Kapil Ganorkar, Soham Mukherjee and Sujit Kumar Ghosh* , Biophysical Chemistry 269 (2021) 106509.
37Syntheses, characterization, multi-acid fluorescence sensing and electroluminescence properties of Cr(ii)-based metallopolymers;, Anil Kumar, Shubham Bawa, Kapil Ganorkar, Sujit Kumar Ghosh, Anasuya Bandyopadhyay; Polym. Chem., 2020,11, 6579-6590
36“Synthesis and characterization of acid-responsive luminescent Fe(II) mettalopolymers of rigid and flexible backbone N-donor multidentate conjugated ligands”; Anil Kumar Shubham Bawa, Kapil Ganorkar, Sujit Kumar Ghosh & Anasuya Bandyopadhyay* Inorganic Chemistry 59 (2020) 1746-1757.
35“Entrapment in micellar assemblies switches the excimer population of potential therapeutic luminophore azapodophylotoxin”; Soham Mukherjee, Smruti Gupta, Kapil Ganorkar, Ajay Kumar & Sujit Kumar Ghosh* Spectrochimica Acta A: Mol. Biomol Spectroscopy 228 (2020) 117723.
34” The consequences of adopting therapeutic luminophore azapodophyllotoxin into BSA: A molecular regulator to control emissive population of two tryptophan residues in carrier protein”; Soham Mukherjee, Kapil Ganorkar, Smruti Gupta, Ajay Kumar, Anuja Singh & Sujit Kumar Ghosh*, Journal of Biomolecular Structure and Dynamics, 38 (2020) 2338-2351
33“Biomimetic systems trigger a benzothiazole based molecular swith to ‘turn on’ fluorescence” Manojkumar Jadhao, Ritika Joshi, Kapil Ganorkar & Sujit Kumar Ghosh*, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 217 (2019), 197-205.
32“Switching of Trp-214 intrinsic rotamer population in Human Serum Albumin: An insight into the aftermath of embracing therapeutic bioorganic luminophore Azapodophyllotoxin into Sudlow site I”; Soham Mukherjee, Kapil Ganorkar, Ajay Kumar, Naina Sehra & Sujit Kumar Ghosh*, Bioorganic Chemistry, 84 (2019) 63-75.
31“Exploration of the ESIPT process in a newly designed potential bioactive thiosemicarbazone Schiff base: Spectroscopic analysis accompanied by molecular optimization and crystallographic study” Kapil Ganorkar, Soham Mukherjee, Sneha Wankar, Ritika Joshi, Chayan Das and Sujit Kumar Ghosh* Journal of Photochemistry and Photobiology A: Chemistry, 371 (2019) 81-90.
30“A Chalcone-Based Potential Therapeutic Small Molecule That Binds to Subdomain IIA in HSA Precisely Controls the Rotamerization of Trp-214” H. Kumar, V. Devaraji, R. Joshi, S. Wankar and Sujit Kumar Ghosh*, ACS Omega, 8 (2018) 10114–10128.
29“A Novel Quinoline-Appended Chalcone Derivative as Potential Plasmodium falciparum Gametocytocide” H. Kumar, I. Wadi, V. Devaraji, C.R Pillai & Sujit Kumar Ghosh* J. Vector Dis. 56 (2019) 189-199.
28“Unveiling the Potential of Unfused Bichromophoric Naphthalimide to Induce Cytotoxicity by Binding to Tubulin: Breaks Monotony of Naphthalimides as Conventional Intercalators” R. Joshi, D. Das Mukherjee, S. Chakrabarty, A. Martin, M. Jadhao, G. Chakrabarti, A. Sarkar, Sujit Kumar Ghosh*, J. Phys. Chem. B 122 (2018) 3680-3695.
27“Is the Sudlow site I of human serum albumin more generous to adopt prospective anti-cancer bioorganic compound than that of bovine: A combined spectroscopic and docking simulation approach” R. Joshi, M. Jadhao, H. Kumar and Sujit Kumar Ghosh*, Biorg. Chem. 75 (2017) 332-346.
26“Unusual Photophysics of Anticancer Azapodophyllotoxin: The Collective Effect of Discrete H-bond Motif Spills the Beans” Sujit Kumar Ghosh*, Ritika Joshi, Soham Mukherjee, Ajay Kumar, Anuja Singh, Michael Concepcion-Santana, J. Photochem. Photobiol. A: Chem. 349 (2017) 49-52.
25“Development of Multifunctional Heterocyclic Schiff Base as a Potential Metal Chelator: A Comprehensive Spectroscopic Approach towards Drug Discovery”, M. Jadhao, C.Das, A. Rawat, H. Kumar, R. Joshi, Sudipta Maiti and Sujit Kumar Ghosh* J. Biol. Inorg. Chem., 22, (2017) 47-59.
24“Conformation controlled turn on – turn off phosphorescence in metal free biluminophore: Thriving the paradox that exists for organic compounds”, R. Joshi, O. R. Meitei, M. Jadhao, H. Kumar and Sujit Kumar Ghosh* Phys. Chem. Chem. Phys. 18 (2016), 27910-27920.
23“Aggregation-Disaggregation Pattern of Photodynamic Active ZnPcS4 and its Interaction with DNA alkylating quinone: Effect of micellar Compactness and Central Metal Ion” M. Jadhao, S. Mukherjee, R. Joshi and H. Kumar & Sujit Kumar Ghosh*, RSC Adv. 6 (2016) 77161-77173.
22“Design, Synthesis and Proticity Inclined Conformational Modulation in Highly Fluorescent Bichromophoric Napthalimide Derivative: Hint Directed Towards RICT”, R. Joshi, O.R. Meitei, H. Kumar, M. Jadhao & Sujit Kumar Ghosh*, J. Phys. Chem. A. 120, (2016) 1000-1011.
21“ESIPT Reaction of Potential Bioactive Heterocyclic Schiff Base: Atomic Visualization Coupled with In vitro Spectroscopy” M. Jadhao, O. R. Meitei, R. Joshi, H. Kumar, C. Das and Sujit Kumar Ghosh* J. Photochem. Photobiol. A: Chem. 326 (2016) 41-49.
20“Interaction of Aluminum Phthalocyanine with Aziridinyl Quinone in Biomimicking Micellar Microenvironment for the Application in Photodynamic Therapy: Effect of Micellar Hydration”, M. Jadhao, P. Ahirkar, R. Joshi, H. Kumar & Sujit Kumar Ghosh*, J. Photochem. Photobiol. A Chem. 316, (2016),62-68.
19“Antihypertensive Activity of a Quinoline Appended Chalcone Derivative and ts Site Specific Binding Interaction with a Relevant Target Carrier Protein”, H. Kumar, V. Devaraji, R. Joshi, M. Jadhao, P. Ahirkar, Prasath. R, P. Bhavana & Sujit Kumar Ghosh*, RSC Adv. 5,(2015), 65496–65513.
18“Surfactant Induced Aggregation–disaggregation of Photodynamic Active Chlorin e6 and Its Relevant Interaction with DNA Alkylating Quinone in a Biomimic Micellar Microenvironment”, M.Jadhao, P. Ahirkar, H. Kumar, R. Joshi, O.R. Meitei & Sujit Kumar Ghosh*, RSC Adv. 5,(2015), 81449–81460.
17“Groove Binding Mediated Structural Modulation and DNA Cleavage by Quinoline Appended Chalcone Derivative”, H. Kumar, V. Devaraji, Prasath. R, M. Jadhao, R. Joshi, P. Bhavana & Sujit Kumar Ghosh*, Spectrochim. Acta Part A Mol. Biomol. Spectrosc. 151, (2015), 605–615.
16“Design, Synthesis, Physicochemical Studies, Solvation, and DNA Damage of Quinoline-Appended Chalcone Derivative: Comprehensive Spectroscopic Approach toward Drug Discovery”, H. Kumar, A. Chattopadhyay, Prasath. R, V. Devaraji, R. Joshi, P. Bhavana, P. Saini & Sujit Kumar Ghosh*, J. Phys. Chem. B. 118, (2014), 7257–7266.
15“Probing single-molecule interfacial electron transfer dynamics of porphyrin on TiO2 nanoparticles”: Yuanmin Wang, Xuefei Wang, Sujit Kumar Ghosh, and H. Peter Lu. J. Am. Chem. Soc. 131, (2009) 1479-1487.
14“Photosensitized reduction and DNA covalent binding of Azridinyl quinones” Antonio E. Alegria, Nadya C. Martinez, Sujit Kumar Ghosh, Carmelo Garcia and Rofel Arce. J. Photochem. Photobiol A. Chemistry 185 (2007) 206-213.
13“Synthesis of 2-(2-Selenocyanato-ethyl)-benzo [de] isoquinoline-1, 3-dione it’s photophysics and interaction with bovine serum albumin: A spectroscopic approach” Sujit Kumar Ghosh, U. Hossen, S. Chattapadhyay & S. C. Bhattacharya. J. Photochem. Photobiol B. Biology 81 (2005) 121-128.
12Quenching of fluorescence of 3, 7-Diamino-2, 8-dimethyl-5-phenyl phenazinium chloride by halides and pseudohalides in mixed micellar media”, by Pijus Kanti Khatua, Sujit Kumar Ghosh and S. C. Bhattacharya, J. Mol. Liquids 124 (2006) 45-50.
11Distribution of quencher ions in ternary system of Igepal / water / carbontetrachloride at Different water pool concentration: A spectroscopic study” Susantamay Nandi, Sujit Kumar Ghosh & S. C. Bhattacharya. Col. Surf. A Phys. Eng. Asp. 268, 2005, 118-123.
10“Characterisation of binary surfactant mixtures (Cetylepyridinium Chloride and Tween 60) in an aqueous medium” Pijus Kanti Khatua, Sujit Kumar Ghosh & S. C. Bhattacharya. J. Dispersion Sci. Tech. 25, 6, 2005, 741-748.
9“Partitioning of Quencher Ions in the Micellar Microenvironment of Polyoxyethylene Nonyl Phenol” Sujit Kumar Ghosh, Pijus Kanti Khatua, Jayanta Kumar Ghosh & S. C. Bhattacharya. Spectrochemica Acta A. 61, 2005, 395-401.
8“Triplet State Interaction of Safranine T with Inorganic Cations in Different Solvents” Pijus Kanti Khatua, Sujit Kumar Ghosh, S. C. Bera & S. C. Bhattacharya. J. Mol. Structure, 757, 2005, 43-48.
7“Photophysics of model lipid membrane of phosphatidicholine using 3, 7- diamino – 2, 8 – dimethyl – 5 – phenyl phenazinium chloride”. Sujit Kumar Ghosh and S.C. Bhattacharya. Chem. Phys. Lipids 131, 2, 2004, 151-158.
6“Physicochemical characteristics of reverse micelle of Igepal in different organic solvents” Sujit Kumar Ghosh, Pijus Kanti Khatua & S. C. Bhattacharya. J. Colloid Interface Sci. 279, 2, 2004, 523-532.
5“Characterization of polyoxyethylene nonyl phenol (Igepal) and its complexation with 3, 7- diamino – 2, 8 – dimethyl – 5 – phenyl phenazinium chloride” Sujit Kumar Ghosh, Pijus Kanti Khatua & S.C. Bhattacharya. J. Colloid Interface Sci. 275, 2004, 623-631.
4“Role of Nonionic Micelles of Tweens in Photovoltage Generation using Fluorescein Dye” Jayanta Kumar Ghosh, Sujit Kumar Ghosh & S. C. Bhattacharya. J. Oleo. Sci. 53, 2, 2004, 73 –74.
3“Effect of Solvent the on the Spectroscopic Behavior of the Dye Safranine T” Pijus Kanti Khatua, Sujit Kumar Ghosh & S. C. Bhattacharya, J. Oleo Sci. 52, 7, 2003, 387-391.
2“Spectroscopic Studies of Reverse Micelles of Igepal in Chloroform” Sujit Kumar Ghosh & S. C. Bhattacharya, J. Mol. Liquids. 106, 2003, 97-109.
1“Aggregation of Nonionic Surfactant Igepal in aqueous Medium: Fluorescence and Light Scattering Studies” Sujit Kumar Ghosh, Pijus Kanti Khatua & S. C. Bhattacharya. Int. J. Mol. Sci. 4, 2003, 562-571.
Sr. No.TitleFunding AgencyRoleYearAmount (in Lakhs INR)
1“Photophysical studies of some selected DNA damage reactions”CSIRPI201217.35 Lakh
2“Physicochemical studies and the identification of DNA damage by porphyrin sensitized alkylating quinones”DSTPI201225.6 Lakh
3“Photosensitizing drugs in model membrane”BITS PilaniPI20112 Lakh
4“Development of low-cost fluorescence spectrometer for industrial and academic application”VNIT, NagpurPI202415 Lakh
DescriptionAuthor(s)PublisherISBNYear
1. “Application of Biodegradable Lipid Composites in Drug Delivery” , Chapter 7, Book: “Advanced Applications of Bio-degradable Green Composites” Vishal Beldar, Ritika Joshi, Sujit Kumar Ghosh, and Manojkumar Jadhao,Materials Research Foundations https://doi.org/10.21741/9781644900659-768 (2020) 156-195
2. “Recent trends in the applications of nanocomposites in cancer theragnostics”, Chapter 12, Book: Green Sustainable Process for chemical and Environmental Engineering and Science Biomedical Applications of Green CompositesRitika Joshi, Manojkumar Jadhao, Sujit Kumar GhoshElsevier ScienceDOI:10.1016/B978-0-323-95169-2.00011-02023
Sr. No.Patent TitleApplication No.DatePresent Staus
1Modified Chimney To Arrest Carbon Dioxide Gas And Carbon Soot20173101621408/06/2017Granted
Sr. No.Title
Sr. No.ResponsibilityInstituteRoleYear
1Head, Department of ChemistryVisvesvaraya National Institute of Technology, Nagpur 4400102024
2
Sr. No.Awards
1Obtained CSIR research fellowship
2Obtained TWAS-CnPq research fellowship
3Obtained MBRS –NIH Post-doctoral fellowship
4Obtained BGSU Research associateship
5Obtained TIFR visiting fellowship
Sr. No.TitleFunding AgencyRoleYearAmount (in Lakhs INR)

Life member L/M-G-32

Indian Society for the Surface science and Technology, Kolkata-700032, India.

Life member L 21473

The Indian Science Congress Association, Govt. of India

Life & Executive member Membership no: 1205

Indian Photobiology Society (IPS)

Annual member (Membership no:30320230)

American Chemical Society (ACS)