Department of Chemistry, VNIT

Dr. Umesh R. Pratap

Brief Bio

Brief Bio
Dr. Umesh Pratap completed his Master's from Dr. Babasaheb Ambedkar Marathwada University with a gold medal (University First rank) and then joined for Ph.D. under the supervision of Prof. R.A.Mane in the same institute. He worked there in the area of biocatalysis for organic synthesis and later moved as an Assistant Professor in Dept. of Chemistry, VNIT Nagpur (2012). Dr. Pratap's area of interest is the biocatalytic transformations, heterocyclic synthesis, and development as well as catalysis of porous organic frameworks

Education

Sr. No.DegreeYearSpecializationUniversity
1M.Sc.2006Organic chemistryDr. Babasaheb Ambedkar Marathwada University, Aurangabad, Maharashtra
2Ph.D.2011Organic chemistryDr. Babasaheb Ambedkar Marathwada University, Aurangabad, Maharashtra

Contact Details

Phone:Email:Address:
Phone No.+91-0712-2801773Email: upratap@chm.vnit.ac.inAssociate Professor, Dept. of Chemistry, Visvesvaraya National Institute of Technology, Nagpur-440 010, Maharashtra.

Research Interest

Research Interest
Organic synthesis
Heterocyclic chemistry
Biocatalysis
Porous organic materials (COP, COF)
Sr. No.TitleFunding AgencyRoleYearAmount (in Lakhs INR)
1Biocatalysis for the development of sustainable organic synthesisSERB, New DelhiPI2013-1732.71
S.No.Paper Citation
1Bhagat, S.; Rout, S.; Bhattacharya, M.; Singh, P.; Karnamkkott, H. S.; Mondal, K. C.; Sankapal, B. R.; Pratap, U. R. Exquisite synthesis of porphyrin-derived covalent organic framework spheres as an electrochemical double-layer capacitor. J. Energy Storage 2026, 143, 119504.
2Wahurwagh, S. A.; Bhagat, S.; Verma, A.; Pratap, U. R. Immobilization of Catalase on Polyhedral Oligomeric Silsesquioxane (POSS)-Based Matrix and Its Catalytical Activity in 3,3′,5,5′-Tetramethylbenzidine (TMB) Oxidation. Macromol. Chem. Phys. 2025, 226 (23), e00296.
3Bhagat, S.; Singh, P.; Nayak, S. S.; Wahurwagh, S.; Pratap, U. R. Fe(III)-Anchored Porphyrin-Based Covalent Organic Framework as a Potent Catalyst for Biginelli Reaction. ChemPlusChem 2025, 90, e202500605.
4Verma, A.; Nayak, B.; Jaiswal, P.; Bhagat, S.; Pratap, U. R. Advanced palladium-hybrid covalent organic framework: A highly efficient catalyst for sustainable cascade synthesis of chromeno[2,3-d]pyrimidine-8-amines. Reactive Funct. Polym. 2025, 216, 106424.
5Wahurwagh, S. A.; Bhagat, S.; Talmale, A. S.; Zodape, S. P.; Pratap, U. R. Integration of ZnO into polyhedral oligomeric silsesquioxane (POSS) for enhanced adsorption and removal of malachite green dye from aqueous solution. J. Inorg. Organomet. Polym. Mater. 2025, 35(6), 4285–4299.
6Bhagat, S.; Wahurwagh, S.; Verma, A.; Pratap, U. R. Harnessing synergy: Immobilized Cu(II) and Pd(II) species on magnetic silica-coated copper ferrite for A3 and Sonogashira coupling reactions. Appl. Surf. Sci. 2025, 687, 162264.
7Shelke, B. N.; Jopale, M. K.; Pratap, U. R.; Kategaonkar, A. H. Optimization of orange G and indigo carmine dye sequestration by incense stick ash: Characterisation, isotherm, and kinetic analysis. Biomass Convers. Biorefin. 2024, 14(20), 25251–25262.
8Garg, A.; Pratap, U. R.; Banerjee, A.; Ghosh, S. K. Development of a dual-state emissive naphthalimide-based organic probe: Interesting synergistic effects from the solid state to the solution phase. Cryst. Growth Des. 2024, 24(18), 7632–7643.
9Verma, A.; Sahay, S. S.; Nayak, S. S.; Nayak, B.; Pratap, U. R. A green and metal-free one-pot three-component synthesis of thiazolobenzimidazoles in sustainable deep eutectic solvent. Inorg. Chem. Commun. 2024, 166, 112613.
10Dani, S. H.; Gouda, A.; Verma, A.; Pratap, U. R. Zinc-Embedded Porous Organic Framework Catalyzed Synthesis of 2-Phenyl Benzimidazoles. ChemistrySelect 2023, 8(29), e202302193.
11Bhagat, S.; Dani, S.; Verma, A.; Dharavath, R.; Pratap, U. R. Cu@CTF as an efficient heterogeneous catalyst in click reaction between azide and alkyne towards disubstituted triazoles. J. Mol. Struct. 2023, 1284, 135350.
12Dani, S. H.; Pratap, U. R. Cu@MTPOF as an Efficient Catalyst for the C–S Coupling of 2-Mercaptobenzimidazole with Aryl Halides and 2-Halobenzoic Acids. Catal. Lett. 2023, 153(6), 1708–1718.
13Jain, A.; Pratap, U. R.; Wankhade, A. V.; Zodape, S. P. An insight into the thermodynamic investigation of important metabolite (KCl)-methyl nicotinate in aqueous solution at various temperatures. Chem. Thermodyn. Therm. Anal. 2022, 6, 100055.
14Singh, R. P.; Khagar, P. S.; Mourya, A. K.; Pratap, U. R.; Wankhade, A. V. Synthesis of Ag2V4O11 nanoflakes mediated photoactivation of peroxymonosulfate ion for enhanced dye degradation and intrinsic bactericidal activity. Mater. Sci. Semicond. Process. 2022, 143, 106526.
15Khagar, P.; Zodape, S.; Pratap, U. R.; Maldhure, A.; Gaikwad, G. Sustainable hybrid nanomaterials for environmental remediation and agricultural advancement. In Biogenic Sustainable Nanotechnology Trends and Progress; 2022; pp 267–292.
16Jain, A.; Shende, V. S.; Kawadkar, D. V.; Wankhade, A. V.; Pratap, U. R.; Zodape, S. P. Studies of solute–solvent interactions of imidazolium-based ionic liquid in water and aqueous L-alanine solution via volumetric and compressibility properties at T = (293.15–313.15) K. J. Chem. Thermodyn. 2021, 162, 106561.
17Shende, V. S.; Pratap, U. R.; Wankhade, A. V.; Zodape, S. P. Investigation of molecular interactions of a drug Isoprenaline Hydrochloride-L-alanine in water at different temperatures. J. Mol. Liq. 2021, 337, 116580.
18Khagar, P.; Pratap, U. R.; Zodape, S. P.; Wankhade, A. V. Self-assembled CoSe2 Microspheres with Intrinsic Peroxidase Mimicking Activity for Efficient Degradation of Variety of Dyes. ChemistrySelect 2021, 6(20), 5043–5051.
19Warkhade, S. K.; Singh, R. P.; Das, R. S.; Maldhure, A.; Pratap, U. R.; Wankhade, A. V. CoSe2 nanoflakes: An artificial nanoenzyme with excellent peroxidase like activity. Inorg. Chem. Commun. 2021, 126, 108461.
20Shende, V. S.; Pratap, U. R.; Wankhade, A. V.; Zodape, S. P. Investigation of the thermodynamic and compressibility properties of antihypertensive drug Hydralazine hydrochloride in aqueous and aqueous amino acids solutions at various temperatures. J. Mol. Liq. 2021, 321, 114755.
21Shrivas, P.; Zodape, S.; Wankhade, A.; Pratap, U. Facile synthesis of benzazoles through biocatalytic cyclization and dehydrogenation employing catalase in water. Enzyme Microb. Technol. 2020, 138, 109562.
22Shrivas, P.; Pandey, R.; Zodape, S.; Wankhade, A.; Pratap, U. R. Green synthesis of pyranopyrazoles via biocatalytic one-pot Knoevenagel condensation–Michael-type addition–heterocyclization cascade in non-aqueous media. Res. Chem. Intermed. 2020, 46(5), 2805–2816.
23Shrivas, P.; Pratap, U. R. Biocatalytic one-pot three-component synthesis of 4H-chromene derivatives in non-aqueous medium. Chem. Pap. 2019, 73(5), 1301–1307.
24Warkhade, S. K.; Das, R. S.; Gaikwad, G. S.; Pratap, U. R.; Zodape, S. P.; Wankhade, A. V. A facile microwave assisted fabrication of nano Ag2ZrO3: An efficient visible light harvesting photocatalyst. Environ. Prog. Sustain. Energy 2019, 38(3), e13071.
25Warkhade, S. K.; Zodape, S. P.; Pratap, U. R.; Wankhade, A. V. Rutile TiO2/CoSe nanocomposite: An efficient photocatalyst for photodegradation of model organic dyes under visible light irradiation. J. Mol. Liq. 2019, 279, 434–443.
26Warkhade, S. K.; Zodape, S. P.; Pratap, U. R.; Wankhade, A. V. Microwave-assisted optimized route for the synthesis of CoSe2 nanoflakes: an efficient material for adsorptive removal of Rhodamine B. J. Chem. Technol. Biotechnol. 2018, 93(10), 2868–2877.
27Kawadkar, D. V.; Pratap, U. R.; Wankhade, A. V.; Zodape, S. P. Molecular interactions of Pyridinium DIL with D–glucose: Volumetric, acoustic and viscometric approach. J. Mol. Liq. 2018, 257, 132–143.
28Warkhade, S. K.; Chaurasiya, V.; Rawat, M.; Pratap, U. R.; Wankhade, A. V. Nano-Nickel Aluminates: A Sustainable Nanocatalyst for Solvent-Free Acetylation of Alcohols Phenols and Amines. ChemistrySelect 2018, 3(9), 2515–2522.
29Bhattacharya, D. M.; Kawadkar, D. V.; Pandhurnekar, C. P.; Pratap, U. R.; Zodape, S. P. Investigation of Volumetric and Acoustic Properties of Procainamide Hydrochloride in Aqueous Binary and (Water + Amino Acid) Ternary Mixtures at Different Temperatures. J. Chem. Eng. Data 2017, 62(12), 4083–4092.
30Khillare, L. D.; Pratap, U. R.; Bhosle, M. R.; Bhalerao, M. B.; Mane, R. A. Syntheses of biodynamic heterocycles: baker’s yeast-assisted cyclocondensations of organic nucleophiles and phenacyl chlorides. Res. Chem. Intermed. 2017, 43(8), 4327–4337.
31Warkhade, S. K.; Gaikwad, G. S.; Zodape, S. P.; Maldhure, A. V.; Pratap, U. R.;Wankhade, A. V. Low temperature synthesis of pure anatase carbon doped titanium dioxide: An efficient visible light active photocatalyst. Mater. Sci. Semicond. Process. 2017, 63, 18–24.
32Kawadkar, D. V.; Pratap, U. R.; Wankhade, A. V.; Zodape, S. P. Influence of D-glucose on solvation behavior of Bis C3 (mim) Br2. J. Mol. Liq. 2017, 232, 94–104.
33Shrivas, P.; Punyapreddiwar, N.; Wankhade, A. V.; Zodape, S.; Pratap, U. R. Baker’s yeast catalyzed Henry reaction: Biocatalytic C-C bond formation. Iran. J. Catal. 2017, 7(4), 337–340.
34Punyapreddiwar, N. D.; Zodape, S. P.; Wankhade, A. V.; Pratap, U. R. Conjugate addition of malononitrile on chalcone: Biocatalytic C—C bond formation. J. Mol. Catal. B Enzym. 2016, 133, 124–126.
35Jawale, D. V.; Pratap, U. R.; Bhosale, M. R.; Mane, R. A. One-Pot Three-Component Synthesis of 2-Amino Pyrimidines in Aqueous PEG-400 at Ambient Temperature. J. Heterocycl. Chem. 2016, 53(5), 1626–1630.
36Bhattacharya, D. M.; Pratap, U. R.; Wankhade, A. V.; Zodape, S. P. Volumetric and ultrasonic approach in the investigation of critical micellar phenomenon of amphiphilic drugs in aqueous solutions at different temperatures. J. Mol. Liq. 2016, 214, 117–127.
37Bhosle, M. R.; Mali, J. R.; Pratap, U. R.; Mane, R. A. An efficient synthesis of new pyrazolines and isoxazolines bearing thiazolyl and etheral pharmacophores. Bull. Korean Chem. Soc. 2012, 33(6), 2012–2016.
38Jawale, D. V.; Pratap, U. R.; Mane, R. A. An alternative synthetic route for an antidiabetic drug, rosiglitazone. Bioorg. Med. Chem. Lett. 2012, 22(2), 924–928.
39Jawale, D. V.; Pratap, U. R.; Rahuja, N.; Srivastava, A. K.; Mane, R. A. Synthesis and antihyperglycemic evaluation of new 2,4-thiazolidinediones having biodynamic aryl sulfonylurea moieties. Bioorg. Med. Chem. Lett. 2012, 22(1), 436–439.
40Pratap, U. R.; Jawale, D. V.; Netankar, P. D.; Mane, R. A. Baker’s yeast catalyzed one-pot three-component synthesis of polyfunctionalized 4H-pyrans. Tetrahedron Lett. 2011, 52(44), 5817–5819.
41Jawale, D. V.; Pratap, U. R.; Mali, J. R.; Mane, R. A. Silica chloride catalyzed one-pot synthesis of fully substituted pyrazoles. Chin. Chem. Lett. 2011, 22(10), 1187–1190.
42Jawale, D. V.; Pratap, U. R.; Mali, J. R.; Mane, R. A. Synthetic Route for New (Z)-5-[4-(2-Chloroquinolin-3-yl) Methoxy]benzylidinethiazolidine-2,4-diones. Bull. Korean Chem. Soc. 2011, 32(7), 2171–2177.
43Jawale, D. V.; Pratap, U. R.; Lingampalle, D. L.; Mane, R. A. Dicationic ionic liquid mediated synthesis of 5-arylidine-2,4-thiazolidinediones. Chin. J. Chem. 2011, 29(5), 942–946.
44Pratap, U. R.; Jawale, D. V.; Bhosle, M. R.; Mane, R. A. Saccharomyces cerevisiae catalyzed one-pot three component synthesis of 2,3-diaryl-4-thiazolidinones. Tetrahedron Lett. 2011, 52(14), 1689–1691.
45Pratap, U. R.; Jawale, D. V.; Londhe, B. S.; Mane, R. A. Baker’s yeast catalyzed synthesis of 1,4-benzothiazines, performed under ultrasonication. J. Mol. Catal. B: Enzym. 2011, 68(1), 94–97
46Karale, S. N.; Pratap, U. R.; Mahalle, S. R.; Mane, R. A. A convenient synthesis of novel 2,3,4-trisubstituted 1,5-benzothiazepines bearing a sulfonyl pharmacophore. J. Sulfur Chem. 2011, 32(4), 303–309.
47Pratap, U. R.; Jawale, D. V.; Waghmare, R. A.; Lingampalle, D. L.; Mane, R. A. Synthesis of 5-arylidene-2,4-thiazolidinediones by Knoevenagel condensation catalyzed by baker’s yeast. New J. Chem. 2011, 35(1), 49–51.
48Jawale, D. V.; Pratap, U. R.; Mulay, A. A.; Mali, J. R.; Mane, R. A. Synthesis of New dihydropyrimidinones catalysed by dicationic ionic Liquid. J. Chem. Sci. 2011, 123(5), 645–65
49Londhe, B. S.; Pratap, U. R.; Mali, J. R.; Mane, R. A. Synthesis of 2-arylbenzothiazoles catalyzed by biomimetic catalyst, β-Cyclodextrin. Bull. Korean Chem. Soc. 2010, 31(8), 2329–2332.
50Mali, J. R.; Pratap, U. R.; Jawale, D. V.; Mane, R. A. Water-mediated one-pot synthetic route for pyrazolo[3,4-b]quinolines. Tetrahedron Lett. 2010, 51(30), 3980–3982.
51Jawale, D. V.; Lingampalle, D. L.; Pratap, U. R.; Mane, R. A. One-pot synthesis of 2-aminothiazoles in PEG-400. Chin. Chem. Lett. 2010, 21(4), 412–416.
52Mali, J. R.; Pratap, U. R.; Netankar, P. D.; Mane, R. A. An efficient synthetic route for quinazolinyl 4-thiazolidinones. Tetrahedron Lett. 2009, 50(35), 5025–5027.
53Pratap, U. R.; Mali, J. R.; Jawale, D. V.; Mane, R. A. Bakers’ yeast catalyzed synthesis of benzothiazoles in an organic medium. Tetrahedron Lett. 2009, 50(12), 1352–1354.
DescriptionAuthor(s)PublisherISBNYear
Sr. No.Patent TitleApplication No.DatePresent Staus
1.      Ph.D. students 
     
Sr. no.Name of the studentTitle of the thesisYear of completionCurrent position/Affiliation
1Prabhakar SrivasDevelopment of biocatalytic methods for the synthesis of biodynamic heterocycles2021Senoir Chemistry faculty, Core Academy, Bilaspur
2Shilpa DaniSynthesis, characterization and catalytic applications of porous organic framework based heterogeneous catalysts2025 
3Shivani BhagatSynthesis of triazoles via click chemistry approach2026 
4Ankit VermaDevelopment of novel catalytic methods for the synthesis of value-added bioactive compoundsOngoing 
5
Sneha Wahurwagh
Enzyme Immobilization for Biocatalytical Applications
Ongoing
 
 
6Pankaj GautamDesign of POP for catalysisOngoing 
7Mayur KarnjekarSynthesis and biological screening of hetereocyclesOngoing 
8Harsh ShuklaCovalent organic framework for catalysisOngoing 
9Aditi GargDevelopment of Threragnostic agentsOngoing (Cosupervisor) 
     
2.      Master Students (M.Sc.) 
1Pranita UmatheAsymmetric synthesis of 2-oxazolidinones and β-nitroalcohols2014 
2Priyanka NeheteSynthesis, characterization and applications of metal organic framework2014 
3Saurabh GuptaSynthesis of 5-arylidene thiazolidine-2,4-diones and 3-(3-oxa-1,3-diphenylpropyl) thiazolidine-2,4-diones2015Assistant Teacher
Basic Education Department, Uttar Pradesh
4Ishank AgrawalMicrowave assisted synthesis of 1,2-disubstituted benzimidazoles using tungstic acid as an efficient catalyst2015Junior Works Manager
Ordinance factory Muradnagar
Ministry of Defence, Govt. of India
5Amardeep AwasthiSynthesis of novel quinoline derivatives encompassing sulfonyl benzimidazole2016
Postdoctoral Fellow, Northwestern University, USA: Supervisor, Prof. Rick Silverman
6Twinkle BhatiaEnvironmental benign synthesis of chromene derivatives in deep eutectic solvent2016PhD from IMT Lille Douai, France, Currently at:
7Rajat PandeyBaker’s yeast catalyzed one pot four component synthesis of pyranopyrazoles2017
PhD, IISER Mohali: Currently at Nelson Mandela University, Port Elizabeth as Postdoc Fellow: Supervisor, Prof. Paul Watts
8Seema KumariBiocatalysis and solid acid catalysis for Michael additions and cyclocondensation with chalcones2017
PhD. Aarhus University, Denmark, Currently working as Chemical Analyst at ADNOC Abudhabi
9Komal TayaLipase catalysed C-C bond formation:1,4 addition of malononitrile and ethyl cyanoacetate on α-β unsaturated ketone2018Ph.D. at University of California Santa Barbara, USA
10Adarsh Kumar MouryaImmobilization of lipase on silica coated Co-ferrite and its application as a nanobiocatalyst2019Ph.D. VNIT NAGPUR
11Suhag Singh SahaySynthesis of 2-arylidinethiazolo [3, 2-a]-benzimidazol-3(2H)-one derivative using baker’s yeast as a catalyst2019Ph.D. (SRF) IIT( ISM) Dhanbad
12Ankit VermaSynthesis of quinoline based thiazolobezimidazole and its derivatives2020Ph.D (SRF) VNIT NAGPUR
13Shreya SrivastavaCOF based heterogeneous catalysts for coupling reactions2020
14SameerImmobilization of catalase over silica coated Co-ferrite magnetic nanoparticles2020Faculty at Physicwallah
15Chetana AgaleCovalent organic framework: A support for enzyme immobilisation2021Assistant Professor
16Sayanti SenapatiCopper embedded COP catalysed synthesis of Imidazo-(1,3)-thiazinone derivatives and their docking study2022Junior Scientist, Metlock Pvt Ltd, Nagpur
17Pallavi DubeyDesign, Synthesis and in-silico analysis (Docking study) of thiazolp-benzimidazol-ones2022Junior manager, Aarti Industries, Mumbai
18Sushree Subhasmita NayakDesign, Synthesis and in-silico analysis (Docking study) of newer tetrazole derivatives2023Ph.D. (JRF) NISER Bhubaneswar
19Ashrumochan GoudaPorous organic framework based heterogeneous catalyst for organic transformations2023Ph.D. Univeristy of Buffalo, USA
20Sachdev MuskanSynthesis of Salphen based Covalent Organic Framework for the synthesis of triazoles via Click chemistry approach2024
21Pradumn JaiswalSynthesis and characterization of Pd@PI COF and its catalytical application for the synthesis of chromeno[2,3-d] pyrimidin-8-amine derivatives2024Ph.D. Shiv Nadar Univesristy
22Naresh BahaliaCu(II)-Enhanced Covalent Organic Framework: Efficient and Recyclable Catalyst for Sustainable Synthesis of Imidazo[1,2-a]pyridines2025Faculty at Akaash
23Pranjal SinghFe@ST-COF as an Efficient and Stable Heterogeneous Catalyst for the Synthesis of Polysubstituted Pyridines2025
Sr. No.Title
1International Conference on Energy and Environmental Challenges (CE2C-2019) 18-19th January 2019, Co-Chair
Sr. No.ResponsibilityInstituteRoleYear
1M.Sc. admission committee (CCMN-2025)VNITChairman (CCMN)2025-26
2M.Sc. admission committee (CCMN-2024)VNITCo-chairman2024-25
3Member of Group A non-teaching recruitment Committee (2024)VNITMember2024
4WardenVNITWarden2016-2022
5Faculty mentorVNITMentor2015-16 and 2025-26
6Stock verification officerVNITStock verification officer2013, 2015
7Member of convocation committeeVNITMember2012, 2022, 2023, 2024, 2025
8Departmental exam coordinatorVNITCoordinator2015-17, 2023-onward
9Departmental Ph.D. entrance coordinatorVNITCoordinator2013-16
10Incharge-Organic chemistry LabVNITIncharge2013-17, 2021-onward
11Deparmtental timetable coordinatorVNITCoordinator2012-23
12Coordinator for providing departmental informationVNITCoordinator2014-16
13Member of campus upkeeping committeeVNITMember 2025-26
Sr. No.Awards
1Gold medal (University First rank at M.Sc.) Dr. Babasaheb Ambedkar Marathwada University, 2006
2UGC-JRF and SRF, University Grant Commission, New Delhi,2008-2011
3Best poster award at NSBBOS, Dr. Babasaheb Ambedkar Marathwada University, 2009
Sr. No.TitleFunding AgencyRoleYearAmount (in Lakhs INR)